March 20, 2013

A diet rich in monounsaturated fats may increase pregnancy rates in women who undergo IVF

There are various types of dietary fats:
Saturated fat. This is a type of fat that comes mainly from animal sources of food. Saturated fat raises total blood cholesterol levels and low-density lipoprotein (LDL) cholesterol levels, which can increase your risk of cardiovascular disease. Saturated fat may also increase your risk of type 2 diabetes
Examples of saturated fats are:
  • Fish such as salmon, albacore tuna and sardines
  • Walnuts
  • Flaxx seed oil
  • Fish oil supplements
 Monounsaturated fat. This is a type of fat found in a variety of foods and oils. Studies show that eating foods rich in monounsaturated fats (MUFAs) improves blood cholesterol levels, which can decrease your risk of heart disease. Research also shows that MUFAs may benefit insulin levels and blood sugar control, which can be especially helpful if you have type 2 diabetes. ( source : Mayo Clinic)
Examples of monounsaturated fats are:

  • Canola oil
  • Peanut oil
  • Olives
  • Olive oil
  • Avocados
  • Seeds such as safflower, sunflower and pumpkin
  • Most nuts such as almonds, cashews and peanuts
  • Almond butter, peanut butter and cashew butter
This study looked at dietary habits.and IVF outcomes. Abstract below:

In multivariate-adjusted regression models, higher intakes of total fat and saturated fat were related to fewer metaphase 2 (M2) oocytes retrieved. This association was driven by intake of saturated fat. Women in the highest third of saturated fat intake had, on average, 9.3 (95%CI: 5.9-14.7) mature oocytes while women reporting the lowest intake had 11.6 (95%CI: 8.1-16.7) mature oocytes, (p-trend = 0.03). Polyunsaturated fat consumption was inversely related to embryo quality. Women in the highest third of polyunsaturated fat intake, had a higher proportion of poor quality embryos (p-trend = 0.02) and slow cleaving embryos (p-trend = 0.001) than women in the lowest third of intake. In addition, higher trans fat consumption was associated with a lower proportion of accelerated cleavage embryos (p-trend = 0.03). Higher intakes of monounsaturated fat were related to higher odds of live birth. The odds ratio of a live birth among women with the highest intake of mono-unsaturated fat was 3.45 (95%CI: 1.12-10.62) when compared to women with the lowest intake (p-trend: 0.03).

Chavarro JE Colaci DS, Afeiche M, Gaskins, AJ, Write D, Toth TL, et al. Dietary fat intake and in-vitro fertilization outcomes: saturated fat intake is associated with fewer metaphase 2 oocytes. Hum Reprod 2012;suppl O-200.

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