March 17, 2013

Women with Vitamin D deficiency have lower implantation at IVF: study

Physicians from the Albert Einstein school of medicine in New York measured follicular fluid levels of Vitamin D  in women who underwent follicular fluid aspiration for IVF.

One of their finding was that the follicular fluid Vitamin D level correlated with serum level: women who were Vitamin D deficient also had lower levels of Vitam D in their ovaries.

In addition the study found that although the number of eggs and embryos was the same . the women who were deficient in Vitamin D had much lower implantation rates.

Comments from the authors below:

Improved COH parameters, in the context of higher vitamin D levels, are suggestive of facilitatory implications of FF 25OH-D on ovarian steroidogenesis, albeit insignificantly so; these observations are hence in keeping with published literature.However, in the absence of any significant relationship with ovarian response, our observations may identify endometrial receptivity as the potential target for beneficial influences of higher circulating vitamin D levels.

The author continue....


The observed prevalence of vitamin D insufficiency in an otherwise healthy population is concerning, especially in the context of accruing data on beneficial influences of replete vitamin D stores on multiple physiological processes and the emerging roles of vitamin D insufficiency in a spectrum of diseases. Given our findings, assessment of vitamin D status might be considered as a part of routine infertility workup since appropriate supplementation of those deemed depleted of vitamin D might translate to improved fertility outcome and improved overall health. These latter conjectures merit further assessment by appropriately designed longitudinal studies.

My conclusion is adequatte vitami D supplementation is an essential  in women deficient in Vitamin D who are undergoing IVF.

1 comment:

  1. IVF is the process of fertilization outside the human body. An egg from the female and sperm from the male are combined in a laboratory dish and placed in a suitable environment for fertilization and early growth of the embryo, before it is implanted back into the uterus.

    IVF Cost

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