The objectives of this study out of the Department of Obstetrics & Gynecology, University of Saarland, Homburg/Saar, Germany were to investigate the levels of Homocysteine , Folic acid (FA) and Vit. B12 in serum and Follicular Fluid of IVF patients and to determine whether these substances could be affect ICSI outcome.
In tis study a positive
correlations was found between Folic acid level in Follicular Fluid and the number of
transferred embryos and pregnancy rate (r=0.25; P=0.031; r=0.121; P=0.318). Vit. B12 correlated significant positively with pregnancy (r=0.228; P=0.037).
This was a small study. More larger studies are needed to investigate the role of B12 levels, and B12 supplementation in fertility patient.
Source: Fertility and Sterility - September 2012 (Vol. 98, Issue 3, Supplement, Page S28, DOI: 10.1016/j.fertnstert.2012.07.103)